The Dog Cancer Survival Guide (140 page)

Radiation treatment for incompletely resected soft-tissue sarcomas in dogs. McKnight JA, Mauldin GN, McEntee MC, et al.
J Am Vet Med Assoc
217:205-10, 2000

Prognosis after surgical excision of canine fibrous connective tissue sarcomas. Bostock DE, Dye MT.
Vet Pathol
17:581-8, 1980

Radiotherapy of soft tissue sarcomas in dogs. McChesney SL, Withrow SJ, Gillette EL, et al.
J Am Vet Med Assoc
194:60-3, 1989

Postoperative radiotherapy for canine soft tissue sarcoma. Forrest LJ, Chun R, Adams WM, et al.
J Vet Intern Med
14:578-82, 2000

Efficacy of mitoxantrone against various neoplasms in dogs. Ogilvie GK, Obradovich JE, Elmslie RE, et al.
J Am Vet Med Assoc
198:1618-21, 1991

Phase II evaluation of doxorubicin for treatment of various canine neoplasms. Ogilvie GK, Reynolds HA, Richardson RC, et al.
J Am Vet Med Assoc
195:1580-3, 1989

Soft tissue sarcomas and mast cell tumours in dogs; clinical behaviour and response to surgery. Baker-Gabb M, Hunt GB, France MP.
Aust Vet J
81:732, 2003.

Immunohistochemical and histopathologic features of 14 malignant fibrous histiocytomas from Flat-Coated Retrievers. Morris JS, McInnes EF, Bostock DE, et al.
Vet Pathol
39:473, 2002

Histopathological survey of neoplasms in flat-coated retrievers, 1990 to 1998. Morris JS, Bostock DE, McInnes EF, et al.
Vet Rec
147:291, 2000

Outcome of dogs with high-grade soft tissue sarcomas treated with and without adjuvant doxorubicin chemotherapy: 39 cases (1996-2004). Selting KA, Powers BE, Thompson LJ, et al.
J Am Vet Med Assoc
227:1442, 2005.

Metronomic therapy with cyclophosphamide and piroxicam effectively delays tumor recurrence in dogs with incompletely resected soft tissue sarcomas. Elmslie RE, Glawe P, Dow SW.
J Vet Intern Med
. 22(6):1373-9. 2008

Spaying and neutering

For a provocative look at the health considerations of spaying and neutering, see:
Long-Term Health Risks and Benefits Associated with Spay / Neuter in Dogs
http://www.naiaonline.org/pdfs/LongTermHealthEffectsOfSpayNeuterInDogs.pdf

Factors influencing canine mammary cancer development and postsurgical survival. Schneider R, Dorn CR, Taylor DO.
J Natl Cancer Inst.
1969 Dec;43(6):1249-61.

Hormonal and Sex Impact on the Epidemiology of Canine Lymphoma. Villamil, JA, et al.
J Cancer Epidemiol
. 2009; 2009: 591753.

Endogenous gonadal hormone exposure and bone sarcoma risk. Cooley DM, et al.
Cancer Epidemiol Biomarkers Prev.
2002 Nov;11(11):1434-40.

A population study of neutering status as a risk factor for canine prostate cancer. Bryan JN, et al.
Prostate.
2007 Aug 1;67(11):1174-81.

Castration for treatment of perianal gland neoplasms in the dog. Wilson GP, Hayes HM Jr.
J Am Vet Med Assoc.
1979 Jun 15;174(12):1301-3.

Effect of spaying and timing of spaying on survival of dogs with mammary carcinoma. Sorenmo KU, Shofer FS, Goldschmidt MH.
J Vet Intern Med.
2000 May-Jun;14(3):266-70.

Long -term risks and benefits of pediatric gonadectomy in dogs. Spain CV, Scarlett JM, Houpt KA,
JAVMA.
2004. 224(3):380-387.

Canine prostate carcinoma: epidemiological evidence of an increased risk in castrated dogs. Teske E, et al.
Mol Cell Endocrinol
. 2002 Nov 29;197(1-2):251-5.

Hormonal and Sex Impact on the Epidemiology of Canine Lymphoma, Villamil JA, et al.
J Cancer Epidemiol.
2009; 2009: 591753.

Specific Cancer Tests (excluding cytology and biopsy)

Evaluation of a bladder tumor antigen test as a screening test for transitional cell carcinoma of the lower urinary tract in dogs. Henry CJ, et al.,
Am J Vet Res
. 2003 Aug;64(8):1017-20.

Information about Pet Screen can be found on their website at
www.pet-screen.com

Information about Oncopet can be found on their website at
www.oncopetdiagnostics.com/

Stress, Depression and Psychoneuroimmunology

Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma. Thaker PH, et al.
Nat Med
. 2006 Aug;12(8):939-44. Epub 2006 Jul 23.

The neuroendocrine impact of chronic stress on cancer. Thaker PH, Lutgendorf SK, Sood AK.
Cell Cycle.
2007 Feb 15;6(4):430-3. Epub 2007 Feb 9. Review.

Neuroendocrine influences on cancer biology. Thaker PH, Sood AK.
Semin Cancer Biol.
2008 Jun;18(3):164-70. Epub 2007 Dec 8. Review.

Neuroendocrine modulation of cancer progression. Armaiz- Pena GN, et al.
Brain Behav Immun.
2009 Jan;23(1):10-5. Epub 2008 Jun 27. Review.

Does the pineal gland have a role in the psychological mechanisms involved in the progression of cancer? Callaghan BD.
Med Hypotheses
. 2002 Sep;59(3):302-11.

Stress, cancer and circadian rhythm of melatonin, Kwiatkowski F, et al.
Pathol Biol (Paris).
2005 Jun;53(5):269-72. Epub 2005 Jan 20. Review. French.

Major depression and cancer: the 13-year follow-up of the Baltimore epidemiologic catchment area sample (United States). Gallo JJ, et al.
Cancer Causes Control
. 2000 Sep;11(8):751-8.

Depression and cancer risk: 24 years of follow-up of the Baltimore Epidemiologic Catchment Area sample. Gross AL, Gallo JJ, Eaton WW.
Cancer Causes Control
. 2010 Feb;21(2):191-9. Epub 2009 Nov 3.

How chronic stress exacerbates cancer, Wells, WA.
J Cell Biol.
2006 August 14; 174(4): 476.

Depression and cancer: recent data on clinical issues, research challenges and treatment approaches. Reich M.
Curr Opin Oncol
. 2008 Jul;20(4):353-9. Review.

The social-psychological precursors to cancer. Cooper CL.
J Human Stress
. 1984 Spring;10(1):4-11.

Incidence and perception of psychosocial stress: the relationship with breast cancer. Cooper CL, Cooper R, Faragher EB.
Psychol Med
. 1989 May;19(2):415-22.

Stress, cancer and immunity. New developments in biopsychosocial and psychoneuroimmunologic research. Baltrusch HJ, Stangel W, Titze I.
Acta Neurol (Napoli).
1991 Aug;13(4):315- 27. Review.

Personality Predictors of the Time Course for Lung Cancer Onset, Augustine AA, et al.
J Res Pers
. 2008 December; 42(6): 1448–1455.

Type A stress prone behaviour and breast cancer. Faragher EB, Cooper CL.
Psychol Med
. 1990 Aug;20(3):663-70.

Psychosocial stress and breast cancer: the inter-relationship between stress events, coping strategies and personality. Cooper CL, Faragher EB.
Psychol Med
. 1993 Aug;23(3):653-62.

Surgery

Surgical Interventions is Cancer. Pope ER, in Henry CJ, Higginbotham ML (ed):
Cancer Management in Small Animal Practice
. Missouri. Saunders Elsevier 2010, p 136-145.

Biopsy Principle. Ehrhart NP, Withrow SJ, in Withrow SJ, Vail DM (eds):
Withrow & MacEwen’s Small Animal Clinical Oncology
. Missouri, Saunders Elsevier, 2007, pp 147-153.

Surgical Oncology. Withrow SJ In Withrow SJ, Vail DM (eds):
Withrow & MacEwen’s Small Animal Clinical Oncology
. Missouri, Saunders Elsevier, 2007, pp 157-162.

Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures. Melamed R, Bar-Yosef S, Shakhar G, Shakhar K, Ben- Eliyahu S.
Anesth Analg
. 2003 Nov;97(5):1331-9.

Transitional Cell Carcinoma

Bladder and Urethral Tumors. Henry CJ, in Henry CJ, Higginbotham ML (ed):
Cancer Management in Small Animal Practice
. Missouri. Saunders Elsevier 2010, p 290-296.

Tumors of the urinary system. Knapp DW. Withrow SJ, Vail DM (eds):
Withrow & MacEwen’s Small Animal Clinical Oncology
. St Louis Missouri, Saunders Elsevier, 2007, pp 649-658

Transitional Cell Carcinoma. Bryan JN, in Cote E (2
^nd
ed),
Clinical Veterinary Advisor: Dogs and Cats
. Missouri, Mosby Elsevier, 2011, p 1112-1114.

Management of Transitional Cell Carcinoma. Henry CJ.
Vet Clin Small Anim
33: 597-614, 2003.

Evaluation of a bladder tumor antigen test as a screening test for transitional cell carcinoma of the lower urinary tract in dogs. Henry CJ, Tyler JW, McEntee MC, et al.
Am J Vet Res
64:1017, 2003.

Epidemiologic study of insecticide exposures, obesity, and risk of bladder cancer in household dogs. Glickman LT, Schofer FS, McKee LF, et al.
J Tox Environ Health
28(4):407, 1989.

Herbicide exposure and the risk of transitional cell carcinoma of the urinary bladder in Scottish terrier dogs. Glickman LT, Raghyavan M, Knapp DW et al.
J Am Vet Med Assoc
224:1290- 1297, 2004.

Evaluation of the effect of dietary vegetable consumption on reducing risk of transitional cell carcinoma of the urinary bladder in Scottish Terriers. Raghavan M, Knapp DW, Bonney PL, et al.
J Am Vet Med Assoc.
227(1):94-100. 2005

Clinical evaluation of mitoxantrone and piroxicam in a canine model of human invasive urinary bladder carcinoma. Henry CJ, McCaw DL, Turnquist SE, et al.
Clin Cancer Res
9:906, 2003.

Piroxicam therapy in 34 dogs with transitional cell carcinoma of the urinary bladder. Knapp DW, Richardson RC, Chan TC, et al.
J Vet Int Med
8:273, 1994.

Canine bladder and urethral tumors: a retrospective study of 115 cases (1980-1985). Norris AM, Laing EJ, Valli VEO, et al.
J Vet Intern Med
6(3):145, 1992.

Surgically induced tumor-seeding in eight dogs and two cats. Gilson SD, Stone EA.
J Am Vet Med Assoc
196(11):1811, 1990.

Piroxicam, mitoxantrone, and course fraction radiotherapy for the treatment of transitional cell carcinoma of the bladder in 10 dogs: a pilot study. Poirier VJ, Forrest LJ, Adams WM, et al.
J Am Anim Hosp Assoc
40:131, 2004.

Surgically induced tumor-seeding in eight dogs and two cats. Gilson SD, Stone EA.
J Am Vet Med Assoc
196(11):1811, 1990.

Needle-tract implantation following US-guided fine-needle aspiration biopsy of transitional cell carcinoma of the bladder, urethra, and prostate. Nyland TG, Wallack ST, Wisner ER.
Vet Radiol Ultrasound
43(1):50, 2002.

Evaluation of a bladder tumor antigen test as a screening test for transitional cell carcinoma of the lower urinary tract in dogs. Henry CJ, Tyler JW, McEntee MC, et al.
Am J Vet Res
64:1017, 2003.

Radiographic appearance of pulmonary metastases from transitional cell carcinoma of the bladder and urethra of the dog. Walter PA, Haynes JS, Feeney DA, et al.
J Am Vet Med Assoc
185(4):411, 1984.

Evaluation of carbon dioxide laser ablation combined with mitoxantrone and piroxicam treatment in dogs with transitional cell carcinoma. Upton ML, Tangner CH, Payton ME.
J Am Vet Med Assoc
228:549, 2006.

Prognostic factors in dogs with urinary bladder carcinoma. Rocha TA, Mauldin GN, Patnaik AK, et al.
J Vet Intern Med
14(5): 486-90

Canine transitional cell carcinoma. Mutsaers AJ, Widmer WR, Knapp DW.
J Vet Intern Med
17:136, 2003

Vaccination (infant) and TH2 shift with potential cancer impact

Optimization of vaccine responses in early life: the role of delivery systems and immunomodulators. Kovarik J, Siegrist CA.
Immunol Cell Biol
. 1998 Jun;76(3):222-36. Review.

The generation of Th memory in neonates versus adults: prolonged primary Th2 effector function and impaired development of Th1 memory effector function in murine neonates. Adkins B, Bu Y, Guevara P.
J Immunol
. 2001 Jan 15;166(2):918- 25.

Molecular immunological approaches to biotherapy of human cancers--a review, hypothesis and implications. Becker Y.
Anticancer Res
. 2006 Mar-Apr;26(2A):1113-34. Review.

Development of neonatal Th1/Th2 function. Adkins B.
Int Rev Immunol
. 2000;19(2-3):157-71. Review.

The role of activation-induced cell death in the differentiation of T-helper-cell subsets. Roberts AI, Devadas S, Zhang X, Zhang L, Keegan A, Greeneltch K, Solomon J, Wei L, Das J, Sun E, Liu C, Yuan Z, Zhou JN, Shi Y.
Immunol Res
. 2003;28(3):285-93. Review.