The Dog Cancer Survival Guide (131 page)

Intracranial meningioma with pulmonary metastasis in three dogs, Schulman FY, Ribas JL, Carpenter JL, et al.
Vet Pathol
29:196, 1992.

Primary optic nerve meningioma and pulmonary metastasis in a dog. Dugan SJ, Schwarz PD, Roberts SM, et al.
J Am Anim Hosp Assoc
29:11, 1993.

Current concepts in the diagnosis and treatments of brain tumours in dogs and cats. LeCouteur RA.
J Small Anim Pract
40:411, 1999.

Radiosurgery using a stereotactic headframe system for irradiation of brain tumors in dogs. Lester NV, Hopkins AL, Bova FJ, et al.
J Am Vet Med Assoc
219:1562, 2001.

Primary irradiation of canine intracranial masses. Spugnini EP, Thrall DE, Price GS, et al.
Vet Radiol Ultrasound
41:377, 2000.

Surgery alone or in combination with radiation therapy for treatment of intracranial meningiomas in dogs: 31 cases (1989- 2002). Axlund TW, McGlasson ML, Smith AN.
J Am Vet Med Assoc
221:1597, 2002.

Calcium

Absorption of calcium as the carbonate and citrate salts, with some observations on method. Heaney RP, Dowell MS, Barger- Lux MJ.
Osteoporos Int
. 1999;9(1):19-23.

Calcium supplementation in clinical practice: a review of forms, doses, and indications. Straub DA.
Nutr Clin Pract
. 2007 Jun;22(3):286-96.

Cancer as a disease of civilization

The effect of diet on risk of cancer. Key TJ, et al.
Lancet
. 2002 Sep 14;360(9336):861-8. Review.

Evolution of the human diet: linking our ancestral diet to modern functional foods as a means of chronic disease prevention. Jew S, AbuMweis SS, Jones PJ.
J Med Food
. 2009 Oct;12(5):925-34. Review.

Population causes and consequences of leading chronic diseases: a comparative analysis of prevailing explanations. Stuckler D.
Milbank Q
. 2008 Jun;86(2):273-326. Review.

Disease without borders. Sener SF.
CA Cancer J Clin
. 2005 Jan- Feb;55(1):7-9.

Cancer risk diversity in non-western migrants to Europe: An overview of the literature. Arnold M, Razum O, Coebergh JW.
Eur J Cancer.
2010 Sep;46(14):2647-59.

Testicular cancer risk in first- and second-generation immigrants to Denmark. Myrup C, et al.
J Natl Cancer Inst.
2008 Jan 2;100(1):41-7. Epub 2007 Dec 25.

Migrant studies aid the search for factors linked to breast cancer risk. Nelson NJ.
J Natl Cancer Inst.
2006 Apr 5;98(7):436-8.

[Mortality among non-western migrants in The Netherlands] Mackenbach JP, et al.
Ned Tijdschr Geneeskd.
2005 Apr 23;149(17):917-23.

Origins and evolution of the Western diet: health implications for the 21st century. Cordain L, et al.
Am J Clin Nutr.
2005 Feb;81(2):341-54. Review.

Between and within: international perspectives on cancer and health disparities. Jones LA, et al.
J Clin Oncol.
2006 May 10;24(14):2204-8. Review.

The rising burden of cancer in the developing world. Kanavos P.
Ann Oncol
. 2006 Jun;17 Suppl 8:viii15-viii23. Review.

The exploding worldwide cancer burden: the impact of cancer on women. Wilson CM, Tobin S, Young RC.
Int J Gynecol Cancer
. 2004 Jan-Feb;14(1):1-11. Review.

Cancer Initiation, Promotion and Progression

Mutation-selection networks of cancer initiation: tumor suppressor genes and chromosomal instability. Komarova NL, et al.,
J Theor Biol
. 2003 Aug 21;223(4):433-50.

Genome maintenance mechanisms for preventing cancer. Hoeijmakers JH.
Nature
. 2001 May 17;411(6835):366-74. Review.

Cancer initiation and progression: an unsimplifiable complexity. Grizzi F, et al.
Theor Biol Med Model
. 2006 Oct 17;3:37.

Cancer as a complex adaptive system. Schwab ED and Pienta KJ.
Med Hypotheses
. 1996 Sep;47(3):235-41.

“Blazing a genetic trial.” Pines, M.
Howard Hughes Medical Institute
.
http://www.hhmi.org/genetictrail/d100.html
. Retrieved on 2010-6-25.

Cancer-related inflammation. Mantovani A, et al.,
Nature
. 2008 Jul 24;454(7203):436-44. Review.

Molecular pathways and targets in cancer-related inflammation. Mantovani A, et al.,
Ann Med
. 2010 Apr;42(3):161-70. Review.

The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance. Allavena P, et al.
Immunol Rev
. 2008 Apr; 222:155-61. Review.

Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Colotta F, et al.,
Carcinogenesis.
2009 Jul;30(7):1073-81.

Emergentism as a default: cancer as a problem of tissue organization. Soto AM and Sonnenschein C.
J Biosci
. 2005 Feb;30(1):103-18. Review.

A Malignant Flame, Stix, G.,
Scientific American Special
. 2008; 18(3): 48-55.

Carbohydrates and sugars

Tumors show enhanced dependency on glucose and glycolytic pathway. Dwarakanath BS and Huilgol NG.
J Can Res Ther
[serial online] 2009 [cited 2010 Apr 2];5:1.

Why do cancers have high aerobic glycolysis? Gatenby RA and Gillies RJ.
Nat Rev Cancer
. 2004 Nov;4(11):891-9. Review.

Metabolic changes during carcinogenesis: potential impact on invasiveness. Smallbone K, et al.
J Theor Biol
. 2007 Feb 21;244(4):703-13.

The glycolytic phenotype in carcinogenesis and tumor invasion: insights through mathematical models. Gatenby RA and Gawlinski ET.
Cancer Res.
2003 Jul 15;63(14):3847-54.

Cancer’s sweet tooth: the Janus effect of glucose metabolism in tumorigenesis. Ashrafian H.
Lancet
. 2006 Feb 18;367(9510):618-21.

Diabetes and Cancer. Gatenby R, Masur, K. (Witten) (eds),
Front Diabetes
. Basel, Karger, 2008, vol 19, pp 59-70.

Carcinogens in the Air

An alternative approach for investigating the carcinogenicity of indoor air pollution: pets as sentinels of environmental cancer risk. J A Bukowski and D Wartenberg.
Environ Health Perspect
. 1997 December; 105(12): 1312–1319.

Environmental tobacco smoke and canine urinary cotinine level, Bertone-Johnson, E.R. et al.
Environ Res
. 2008 March; 106(3): 361–364.

Passive Smoking and Canine Lung Cancer Risk, John S. Reif, et al.
Am. J. Epidemiol
. (1992) 135 (3): 234-239.

Carcinogenicity studies of inhaled cigarette smoke in laboratory animals: old and new. Hecht SS.
Carcinogenesis.
2005 Sep;26(9):1488-92. Epub 2005 Jun 1. Review. Erratum in:
Carcinogenesis.
2005 Nov;26(11):2029.

The following is an article which concludes that cigarette smoke does not cause cancer in the animals studied, (by the way, it’s funded by Lorillard Tobacco Company):
A review of chronic inhalation studies with mainstream cigarette smoke, in hamsters, dogs, and nonhuman primates. Coggins CR.
Toxicol Pathol
. 2001 Sep-Oct;29(5):550-7. Review.

Metabolic activation of carcinogenic aromatic amines by dog bladder and kidney prostaglandin H synthase. Wise RW, et al.
Cancer Res
. 1984 May;44(5):1893-7.

Cancer risk assessment, indicators, and guidelines for polycyclic aromatic hydrocarbons in the ambient air. Boström CE, et al.
Environ Health Perspect
. 2002 Jun;110 Suppl 3:451-88. Review.

Role of radical cations in aromatic hydrocarbon carcinogenesis. Cavalieri, E and Rogan, E.
Environ Health Perspect
. 1985 December; 64: 69–84.

Nitrated polycyclic aromatic hydrocarbons: a risk assessment for the urban citizen. Möller L, Lax I, Eriksson LC.
Environ Health Perspect
. 1993 Oct;101 Suppl 3:309-15.

Indoor levels of polycyclic aromatic hydrocarbons in homes with or without wood burning for heating. Gustafson P, Ostman C, Sällsten G.
Environ Sci Technol
. 2008 Jul 15;42(14):5074- 80.

Carcinogens and Synergy

Gene induction studies and toxicity of chemical mixtures. Mumtaz MM, et. al.
Environ Health Perspect
. 2002 Dec;110 Suppl 6:947-56.

Public health challenges posed by chemical mixtures. Hansen H, et. al.
Environ Health Perspect.
1998 December; 106(Suppl 6): 1271–1280.

Mixtures and interactions. Groten JP.
Food Chem Toxicol
. 2000;38(1 Suppl):S65-71. Review.

Biochemical Reaction Network Modeling: Predicting Metabolism of Organic Chemical Mixtures. Mayeno AN, Yang RSH, Reisfeld B.,
Environ. Sci. Technol
., 2005, 39 (14), pp 5363–5371

Development of a research strategy for integrated technologybased toxicological and chemical evaluation of complex mixtures of drinking water disinfection byproducts. Simmons JE, et. al.
Environ Health Perspect
. 2002 December; 110(Suppl 6): 1013–1024.

Environmental causes of cancer: endocrine disruptors as carcinogens. Soto AM and Sonnenschein C.
Nat Rev Endocrinol
. 2010 Jul;6(7):363-70. Epub 2010 May 25. Review.

Endocrine-disrupting chemicals: an Endocrine Society scientific statement. Diamanti-Kandarakis E, et. al.
Endocr Rev.
2009 Jun;30(4):293-342. Review.

Fifteen years after “Wingspread”--environmental endocrine disrupters and human and wildlife health: where we are today and where we need to go. Hotchkiss AK, et. al.
Toxicol Sci
. 2008 Oct;105(2):235-59. Epub 2008 Feb 16. Review.

Carcinogen Avoidance after a Cancer Diagnosis

A conundrum in molecular toxicology: molecular and biological changes during neoplastic transformation of human cells. Milo GE, et al.
Cell Biol Toxicol
. 1995 Dec;11(6):329-45. Review.

Diminished DNA repair and elevated mutagenesis in mammalian cells exposed to hypoxia and low pH. Yuan J, et al.
Cancer Res
. 2000 Aug 15;60(16):4372-6.

Genetic instability induced by the tumor microenvironment. Reynolds TY, Rockwell S, Glazer PM.
Cancer Res
. 1996 Dec 15;56(24):5754-7.

Mutagenesis induced by the tumor microenvironment. Yuan J, Glazer PM.
Mutat Res
. 1998 May 25;400(1-2):439-46. Review.

Chemotherapy

Chemotherapy. Rodriquez CO, Rankin WV, Henry CJ, et al, in Henry CJ, Higginbotham ML (ed):
Cancer Management in Small Animal Practice
. Missouri. Saunders Elsevier 2010, p 101- 121.

Managing Oncologic Emergencies. Dhaliwal RS, Wiebe VJ, Simonson E, et al, in Henry CJ, Higginbotham ML (ed):
Cancer Management in Small Animal Practice
. Missouri. Saunders Elsevier 2010, p 122-135

Cancer chemotherapy. Chun R, Garrett LD, Vail DM, in Withrow SJ, Vail DM (eds):
Withrow & MacEwen’s Small Animal Clinical Oncology
. Missouri, Saunders Elsevier, 2007, pp 163- 192.

Impact of chemotherapeutic dose intensity and hematologic toxicity on first remission duration in dogs with lymphoma treated with a chemoradiotherapy protocol. Vaughan A, Johnson JL, Williams LE.
J Vet Intern Med
21(6):1332-9, 2007.

Prophylactic trimethoprim-sulfadiazine during chemotherapy in dogs with lymphoma and osteosarcoma: a double-blind, placebo-controlled study. Chretin JD, Rassnick KM, Shaw NA, et al.
J Vet Intern Med
21(1):141-8, 2007.

Risk factors for sterile hemorrhagic cystitis in dogs with lymphoma receiving cyclophosphamide with or without concurrent administration of furosemide: 216 cases (1990-1996). Charney SC, Bergman PJ, Hohenhaus AE, et al.
J Am Vet Med Asso
c.222(10):1388-93, 2003.

Metronomic therapy with cyclophosphamide and piroxicam effectively delays tumor recurrence in dogs with incompletely resected soft tissue sarcomas. Elmslie RE, Glawe P, Dow SW.
J Vet Intern Med
. 22(6):1373-9, 2008.

Safety of concurrent administration of dexrazoxane and doxorubicin in the canine cancer patient. FitzPatrick WM, Dervisis NG. Kitchell B.
Veterinary and Comparative Oncology
, 8: 273– 282. 2010

Acute reactions in dogs treated with doxorubicin: increased frequency with the use of a generic formulation. Phillips BS, Kraegel SA, Simonson E, et al.
J Vet Intern Med
. 12(3):171-2, 1998.

Multi-center, placebo-controlled, double-blind, randomized study of oral toceranib phosphate (SU11654), a receptor tyrosine kinase inhibitor, for the treatment of dogs with recurrent (either local or distant) mast cell tumor following surgical excision. London CA, Malpas PB, Wood-Follis SL, et al.
Clin Cancer Res
. Jun 1;15(11):3856-65, 2009.