"A prion." Lauren touched the diagram of the molecule.
Could this indeed be the cause?
She pondered the possibility. The word
prion
was scientific shorthand for "proteinaceous infectious particle." The role of prions in disease had only been documented within the last decade, earning a U.S. biochemist the 1997 Nobel Prize. Prion proteins were found in all creatures, from humans down to single-celled yeast. Though usually innocuous, they had an insidious duality to their molecular structure, a Jekyll-and-Hyde sort of thing. In one form, they were safe and friendly to a cell. But the same protein could fold and twist upon itself, creating a monster that wreaked havoc on cellular processes. And the effect was cumulative. Once a twisted prion was introduced into a host, it would begin converting the body's other proteins to match, which in turn converted its neighbors, spreading exponentially through the host's systems. Worse, this host could also pass the process to another body, a true infectious phenomenon.
Prion diseases had been documented both in animals and man: from scabies in sheep to Creutsfeldt-Jacob disease in humans. The most well-known prion disease to date was one that
crossed
between species. Dr. Reynolds had mentioned it in his letter: bovine spongiform encephalopathy, or more commonly, mad cow disease.
But these human diseases were more of a degenerative nature, and none were known to be transmitted so readily.
Still, that did not rule out prions as a possibility here. She had read research papers on prions and their role in genetic mutations and more severe manifestations. Was something like that happening here? And what about airborne transmission? Prions were particulate and subviral in size, so since certain viruses could be airborne, why not certain prions?
Lauren stared at the modeled protein on the computer screen and reached for her desk phone. As she dialed, an icy finger ran up her spine. She prayed her former student was mistaken.
The phone rang on the other end, and after a moment, it was answered. "Dr. Reynolds, proteonomics lab."
"Xavier?"
"Yes?"
"This is Dr. O'Brien."
"Dr. O'Brien!" The man began talking animatedly, thanking her, thrilled.
She cut him off. "Xavier, tell me more about this protein of yours." She needed as much information from him as possible, the sooner the better. If there was even a minute possibility that Dr. Reynolds was correct...
Lauren bit back a shudder as she stared at the crablike molecule on her computer monitor. There was one other fact she knew about prion-triggered diseases.
There were no known cures.
9:18 A.M.
AMAZON JUNGLE
Nate looked over Olin Pasternak's shoulder. The CIA's communications expert was growing ever more frustrated with the satellite computer system. Beads of sweat bulleted his forehead, both from the morning's steaming heat and his own consternation.
"Still no feed...goddamn it!" Olin chewed his lower lip, eyes squinting.
"Keep trying," Frank urged on the other side.
Nate glanced to Kelly, who stood beside her brother. Her eyes were haunted and dull. Nate had heard various versions of last night's attack: the strange swarm of giant locusts attracted to the camp by the burning Ban-ali marker. It was too horrible to imagine, impossible, but Jorgensen's death made it all too real.
Once the entire group had been reassembled at the swamp-side camp last night, the Ranger team had remained on guard. The group kept a posted watch throughout the night, in and around the surrounding forest, alert for any danger, watchful for any flare of flames, ears keened for the whine of locusts. But nothing happened. The few hours until dawn had been uneventful.
As soon as the communication satellite was in range, Olin had set about trying to reach the States and to relay messages to the Wauwai field base. It was vital to radio the change in plans to all parties. With unknown hunters dogging their trail, it was decided to continue with the goal of rafting across the swamp. Captain Waxman hoped to get a couple of days' jump on his pursuers, leave their trackers traipsing around the swamp on foot. Once across, Waxman would keep a constant watch on the waters for any Ban-ali canoes and keep the group intact on the far shore until the evac helicopter could arrive. He planned to trade each civilian with another Ranger from the field base at the mission. With these new forces, he would continue on Gerald Clark's trail.
There was only one problem with his plan.
"I'm gonna have to rip the laptop down to the mother-board," Olin said. "Something is damnably fritzed. Maybe a faulty chip or even a loose one knocked out of place by the manhandling these past two days. I don't know. I'll have to tear it down and check it all."
Waxman had been speaking with his staff sergeant, but he overheard Olin. The captain stepped nearer. "We don't have time for that. The third raft is ready, and it'll take a good four hours to cross the waters. We need to get moving."
Nate glanced to the swamp's edge and saw four Rangers positioning the newly constructed raft so that it floated beside the two prepared last night. The additional raft was necessary to carry everyone in their expanded party.
Olin hovered over his computer and satellite dish with a small screwdriver. "But I've not been able to reach anyone. They won't know where we are." He wiped his forehead with the back of his wrist. His features were pale.
Zane stood, shifting his feet uneasily and rubbing at a Band-Aid on his cheek that covered a locust bite. "We could send someone back and retrieve Jorgensen's pack with the military radio," he suggested.
Everyone began talking at once, arguing both sides.
"We'd lose another day waiting." "We'd risk more of our people." "We need to reach
someone
!" "Who knows if his radio will even work, what with all those locusts. They could've chewed through the wiring and--"
Waxman interrupted, his voice booming. "There is no reason to panic!" He directed his comment to all of them. "Even if we can't raise the outside, the field base knows our rough location from yesterday's report. When the Brazilian evac copter comes tomorrow as previously arranged, we'll hear it--even from across the swamp. We can send up orange smoke flares to draw their attention to our new location."
Nate nodded. He had not participated in the argument. In his mind, there was only one way to go--
forward
.
Waxman pointed to Olin. "Pack it up. You can work on the problem once we're on the far side."
Resigned, Olin nodded. He returned his tiny screwdriver to his repair kit.
With the matter settled, the others dispersed to gather their own gear, readying for the day's journey.
"At least we won't have to walk," Manny said, patting Nate on the shoulder as he passed on his way to wake Tor-tor. The jaguar was asleep under a palm, oblivious to the world after last night's trek.
Nate stretched a kink from his neck and approached Professor Kouwe. The Indian shaman stood near the swamp, smoking his pipe. His eyes were as haunted as Kelly's had been. When Nate and Corporal Warczak had met the fleeing group on the trail, the professor had been unusually quiet and somber, more than could be attributed to the loss of Jorgensen.
Nate stood silently beside his old friend, studying the lake, too.
After a time, Kouwe spoke softly, not looking at Nate. "They sent the locusts...the Ban-ali..." The shaman shook his head. "They wiped out the Yanomamo tribe with the piranha creatures. I've never seen anything like it. It's as if the Blood Jaguar tribe could indeed control the jungle. And if that myth is true, what else?" He shook his head again.
"What's troubling you?"
"I've been a professor of Indian Studies for close to two decades. I grew up in these jungles." His voice grew quiet, full of pain. "I should have known...the corporal...his screams..."
Nate glanced to Kouwe and placed a hand on the man's shoulder. "Professor, you saved everyone with the
tok-tok
powder."
"Not everyone." Kouwe drew on his pipe and exhaled. "I should've thought to relight the Ban-ali symbol before we left the camp. If I had, the young corporal would be alive."
Nate spoke sharply, trying to cut through the man's remorse and guilt. "You're being too hard on yourself. No
amount of study or experience could prepare you to deal with the Ban-ali and their biological attacks. Nothing like it has ever been documented before."
Kouwe nodded, but Nate sensed that the man was hardly convinced.
Captain Waxman called from near the water's edge. "Let's load up! Five to a raft!" He began assigning Rangers and dividing the civilians accordingly.
Nate ended up with Kouwe and Manny, along with Tor-tor. Their two mates were Corporal Okamoto and Private Carrera. The group was forced to wade through the shallows to reach the bamboo-and-log constructions. As Nate heaved himself onboard, he appreciated its sturdy construction. Reaching out, Nate helped Manny guide the large cat atop the bobbing raft.
Tor-tor was not pleased about getting wet. As the cat shook the swamp water from its pelt, the rest of the group mounted their own boats.
On the neighboring raft, Kelly and Frank stood with Captain Waxman, along with corporals Warczak and Yamir. The last five teammates climbed onto the farthest raft. Olin was careful to carry his pack with the satellite gear high above his head. Richard Zane and Anna Fong helped him aboard, flanked by a stoic Tom Graves and a scowling Sergeant Kostos.
Once everyone was mounted, lengths of bamboo were used as poles to push away from shore and through the shallows. But the swamp's banks dropped steeply. Within a hundred feet of the shore, the poles no longer touched bottom, and the paddles were taken up. With four paddles per raft, it allowed one person to rotate out and rest. The goal was to continue straight across without a break.
Nate manned the raft's starboard side as the tiny flotilla slowly drifted toward the far bank. Out on the waters, the distant roar of multiple waterfalls, muffled and threatening, echoed over the swamp lake. Nate
stared, shading his eyes. The highlands across the way remained shrouded in mist: a mix of green jungle, red cliffs, and a fog of heavy spray. Their goal was a narrow ravine between two towering, flat-topped mesas, a yawning misty channel into the highlands. It had been where Clark's last carved message had pointed.
As they glided, the denizens of the swamp noted their passage. A snow-white egret skimmed over the water, a hand span above the surface. Frogs leaped from boggy hummocks with loud splashes, and
hoatzin
birds, looking like some ugly cross between a turkey and a pterodactyl, screeched at them as they circled over their nests atop the palms that grew from the island hummocks. The only inhabitants that seemed pleased with their presence were the clouds of mosquitoes, buzzing with joy at the floating smorgasbord.
"Damned bugs," Manny griped, slapping his neck. "I've had it with flying insects making a meal out of me."
To make matters even worse, Okamoto began to whistle again, tunelessly and without the vaguest sense of rhythm.
Nate sighed. It would be a long trip.
After an hour, the little muddy islands vanished around them. In the swamp's center, the water was deep enough to drown away most of the tiny bits of land and jungle. Only an occasional hummock, mostly bare of trees, dotted the smooth expanse of the swamp's heart.
Here the sun, scorching and bright, shone incessantly down on them.
"It's like a steam bath," Carrera said from the raft's port side.
Nate had to agree. The air was thick with moisture, almost too heavy to breathe. Their speed across the swamp slowed as exhaustion set in. Canteens were passed around and around the raft. Even Tor-tor lounged in the middle of the bamboo planking, his mouth open, panting.
The only consolation was being temporarily free of the
jungle's snug embrace. Here the horizons opened up, and there was a giddy sense of escape. Nate glanced frequently back the way they had come, expecting to see a tribesman on the bank back there, shaking a fist. But there remained no sign of the Ban-ali. The trackers of the ghost tribe remained hidden. Hopefully the group was leaving them behind and getting a few days head start on their pursuers.
Nate was tapped on the shoulder. "I'll take a shift," Kouwe said, emptying his pipe's bowl of tobacco ash into the water.
"I'm okay," Nate said.
Kouwe reached and took the paddle. "I'm not an invalid yet."
Nate didn't argue any further and slid to the raft's stern. As he lounged, he watched their old campsite get smaller and smaller. He reached back for the canteen and caught movement to the right of their raft. One of the bare hummocks, rocky and black, was sinking, submerging so slowly that not a ripple was created.
What the hell?
Off to the left another was sinking. Nate climbed to his feet. As he began to comment on this unusual phenomenon, one of the rocky islands opened a large glassy eye and stared back at him. Instantly Nate knew what he was seeing.
"Oh, crap!"
With his attention focused, he now recognized the armored scales and craggy countenance of a crocodilian head. It was a caiman! A pair of giants. Each head had to be four feet wide from eye to eye. If its head was that big...
"What's wrong?" Private Carrera asked.
Nate pointed to where the second of the two caimans was just slipping under the surface.
"What is it?" the Ranger asked, eyes wide, as confused as Nate had been a moment before.
"Caimans," Nate said, his voice hoarse with shock. "Giant ones!"